It's bloodwork ultimately really, but yes you can start out st maybe 0.5mg twice a week to see if that is enough to take care of sides if not try 1mg twice a week Monday and Thursday. If that doesn't work I have heard of people going as high as 1 mg every other day even up to 1mg everyday but again that depends on how much your actually taking of testosterone. And again lastly the unpopular choice...just lower your testosterone dose. If you start experiencing sides.Or does your unique aromatization rate enable you to use various doses without experiencing elevated estrogen levels and developing gynecomastia? At what point do you need to start using AIs when increasing your T doses?